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Archive for May 28th, 2008

Again, I can’t think of a sensible blog entry…all I know is that I want to let go of this feeling… or feelings… whatever… went to my OB yesterday to get the result of my TVS (Trans-Vaginal Sonography)… and guess what… I have this hormonal disorder that affects approximately 10% of women of reproductive age – I have Polycystic ovaries, also called Polycystic ovarian syndrome (PCOS); Stein-Leventhal syndrome; Polyfollicular ovarian disease… it is a condition wherein there are many small cysts in the ovaries that affects a woman’s ability to get pregnant…

Causes:

Polycystic ovary disease affects hormone cycles. Hormones help regulate the normal development of eggs in the ovaries. It is not completely understood why or how hormone cycles are interrupted, although there are several ideas.

Follicles are sacs within the ovaries that contain eggs. In polycystic ovary disease, there are many poorly developed follicles in the ovaries. The eggs in these follicles do not mature and, therefore, cannot be released from the ovaries. Instead, they form cysts in the ovary.

This can contribute to infertility. The immature follicles and the inability to release an egg (ovulate) are likely caused by low levels of follicle stimulating hormone (FSH), and higher-than-normal levels of male hormones (androgens) produced in the ovary.

Women are usually diagnosed when in their 20s or 30s. Women with this disorder often have a mother or sister who has symptoms similar to polycystic ovary disease.

Symptoms:

If you have polycystic ovary disease, you are likely to have some of the following symptoms:

Ø Abnormal, irregular, or very light or infrequent menstrual periods

Ø Absent periods, usually (but not always) after having one or more normal menstrual periods during puberty (secondary amenorrhea)

Ø Acne that gets worse

Ø Decreased breast size

Ø Development of male sex characteristics (virilization) such as increased body hair, facial hair, a deepening of the voice, male-pattern baldness, and enlargement of the clitorus.

Ø Diabetes

Ø Increased hair growth; body hair may be in a male pattern

Ø Infertility

Ø Poor response to the hormone, insulin (insulin resistance), leading to a build-up of insulin in the blood

Ø Weight gain, or obesity

Possible Complications:

Ø Increased risk of endometrial cancer

Ø Infertility

Ø Obesity-related conditions, such as high blood pressure and diabetes

Ø Possible increased risk of breast cancer

Fortunately, this disease is curable… women who have this condition can get pregnant with the right surgical or medical treatments… pregnancies are usually normal…

Treatment:

Medications used to treat the symptoms of polycystic ovary disease include:

Ø Birth control pills

Ø Clomiphene citrate

Ø Flutamide

Ø Spironolactone

Treatment with clomiphene citrate causes the pituitary gland to produce more FSH. This causes the egg to mature and be released. Sometimes women need stronger fertility drugs to get pregnant.

In women with polycystic ovary disease who also have insulin resistance, glucophage (Metformin), a medication that makes cells more sensitive to insulin, has been shown to make ovulation normal.

Losing weight (which can be difficult) may help to reduce the high insulin levels in the blood. For women with this condition who are overweight, weight loss can reduce insulin resistance, stimulate ovulation, and improve fertility rates.

Click this for pictures and additional information about this hormonal disorder…il try to post my results here soon…

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